Mainz vs Hoffenheim Prediction and Betting Tips | November 21st 2025

Mainz will invite Hoffenheim to the Mewa Arena in the Bundesliga on Friday. The hosts have won just one of their 10 league games and are second-from-the-bottom in the league standings. Die Kraichgauer have fared much better with six wins, and they are sixth in the league table with 19 points. Thanks for the submission! Die Nullfünfer have endured a drop in form, and they are winless in their last six games in all competitions. They met Eintracht Frankfurt in their previous outing before the international break and fell to a 1-0 away loss. The visitors extended their winning streak in the league to four games earlier this month, defeating RB Leipzig 3-1. They conceded in the ninth minute, and goals from Albian Hajdari and Tim Lemperle later in the first half helped them overturn the deficit. Grischa Prömel added the goal after the break. Leipzig had two goals overturned by VAR. Mainz vs Hoffenheim Head-to-Head and Key Numbers The two teams have squared off 34 times in all competitions. The hosts have a narrow lead in the head-to-head record with 15 wins. Die Kraichgauer have 10 wins, and nine games have ended in draws. Both teams registered 2-0 home wins in their league meetings last season. The visitors have outscored Die Nullfünfer 21-8 in 10 league games thus far. Mainz have won just two of their eight games in all competitions, with both registered at home in the UEFA Conference League. Hoffenheim are unbeaten on their travels in the Bundesliga this season, winning four of the five games. The visitors have scored three goals apiece in their last four league games. The hosts have lost just one of their last five league games while recording three wins. Mainz vs Hoffenheim Prediction Die Nullfünfer head into the match in poor form, losing five of their last six league games. Notably, they are unbeaten in their last five home games in this fixture, recording four consecutive wins. Anthony Caci and Maxim Dal will miss this match due to injuries. Nadiem Amiri is back in training but is a major doubt alongside Andreas Hanche-Olsen. Die Kraichgauer have lost just one of their last five games, with that defeat registered against FC St. Pauli on penalties in the DFB-Pokal second round. Thirteen of their 21 goals in the Bundesliga this season have been scored on their travels. Adam Hlozek and Koki Machida are the two confirmed absentees for the visitors. Considering the current form of the two teams and the visitors’ recent goalscoring form, we back Die Kraichgauer to register a win here. Prediction: Mainz 1-2 Hoffenheim Mainz vs Hoffenheim Betting Tips Tip 1: Result Hoffenheim to win Tip 2: Goals Over/Under 2. 5 Goals Over 2. 5 goals Tip 3: Both teams to score Yes Tip 4: At least one goal to be scored in the second half Yes.
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