This AI predicts your disease risks 10 years in advance

### This AI Predicts Your Disease Risks 10 Years in Advance

**By Mudit Dube | Sep 18, 2025**

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A team of scientists has developed a groundbreaking artificial intelligence (AI) tool capable of predicting an individual’s risk for over 1,000 diseases. The innovative system, dubbed **Delphi-2M**, can forecast health changes up to a decade in advance. The research, published in the journal *Nature*, highlights the potential of generative AI to model human disease progression on a large scale.

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### How Delphi-2M Works

Delphi-2M uses algorithmic concepts similar to those found in large language models (LLMs). It predicts the likelihood of developing diseases such as cancer, diabetes, heart disease, and respiratory disorders by analyzing key “medical events” in a patient’s history—like diagnosis dates—and lifestyle factors, including obesity status, smoking or drinking habits, age, and sex.

The AI was trained on anonymized patient data from two major healthcare sources: the UK’s Biobank study, comprising 400,000 participants, and Denmark’s national patient registry, which includes 1.9 million patients.

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### Potential Impact on Personalized Healthcare

Delphi-2M predicts health risks expressed as rates over time, much like weather forecasts. According to Ewan Birney, interim executive director of EMBL, patients could benefit from the tool within a few years. He envisions a future where clinicians use AI tools like Delphi-2M to identify major health risks early and suggest lifestyle changes to mitigate them.

This marks a significant step forward in personalized healthcare and disease prevention strategies.

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### Advantages Over Existing Methods

Birney also emphasized Delphi-2M’s superiority compared to current risk assessment models such as Qrisk. Unlike single-disease models, Delphi-2M can assess multiple diseases simultaneously and provide predictions over an extended time frame.

The research team noted that Delphi-2M’s accuracy in predicting disease rates based on an individual’s past medical history rivals that of existing single-disease models.

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### Future Prospects: Revolutionizing Healthcare with Generative Models

Professor Moritz Gerstung from the German Cancer Research Center described Delphi-2M as a major advancement in understanding human health and disease progression. He believes generative AI models like Delphi-2M could eventually personalize care and anticipate healthcare needs on a much larger scale.

This breakthrough underscores the transformative potential of AI tools in predicting individual health risks and enabling proactive healthcare management.

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*Stay tuned for more updates on how AI is shaping the future of medicine and personalized health.*
https://www.newsbytesapp.com/news/science/delphi-2m-ai-tool-predicts-risk-of-over-1-000-diseases/story